Rasu Shrestha MD


Chief Innovation Officer

As chief innovation officer for UPMC, Dr. Shrestha plays a leading role in driving UPMC’s innovation strategy, serving as a catalyst for transforming the organization into a more patient-focused and economically sustainable system.

Dr. Shrestha also serves as the executive vice president of UPMC Enterprises, the innovation and commercialization arm of UPMC. Through strategic partnerships, joint development agreements and investments in promising health care startups, Dr. Shrestha and the Enterprises team champion the development, implementation and commercialization of innovations that solve complex health care challenges.

Dr. Shrestha has been recognized by Becker’s Hospital Review as one of the 26 “Smartest People in Health IT,” and InformationWeek named him one of the “Top 20 Health IT Leaders Driving Change” and a “Top Healthcare Innovator.” He is a frequent speaker at national and international health care, innovation and technology conferences.

Prior to joining the team at UPMC Enterprises, Dr. Shrestha served as the vice president of medical information technology and medical director of interoperability at UPMC. He previously served as the informatics director at the University of Southern California (USC), where he was also a professor of radiology research at the Keck School of Medicine.

Dr. Shrestha received his medical degree from CCS University in India, completed his fellowship in informatics at the University of London, and earned his master’s in business administration from USC. He serves as the chair of the Informatics Scientific Program Committee at the Radiological Society of North America and is also a longtime member of the Advisory Board of KLAS Research.